Integrative biology has emerged as a reaction against the reductionist approach that has dominated the last age of biology. As biologists have the objective of understanding the cells and their environment, either microbiome or tissue, the inclusion of ecological and evolutive principles in the analysis has been crucial.
Even the synthetic approach, built to understand it, has started to consider the potential of the landscape ecological interactions to design biological systems. This “spatial biology” emerging field, whose objective is to comprehend the adjacency relation role in the cellular communities framing, is becoming a central framework to unify biological systems that would be different the other way.